Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes
Alan Mitchell, Mattia Frontini, Serajul Islam, Suthesh Sivapalaratnam, Anandi Krishnan
This paper identifies 32 genes with altered expression in platelets from MPN patients, linking them to thrombosis and bleeding risks, and suggests clinical applications for risk stratification and treatment tailoring.
bioRxiv · May 23, 2023 · PreprintGenomics