Author

Alef AC Santos

Universidade Cruzeiro do Sul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Bianca CastinoiD· 2 shared Fernanda Teixeira BorgesiD· 2 shared Adriana Aparecida Ferraz CarboneliD· 1 shared Amaro Nunes Duarte NetoiD· 1 shared André Luís Lacerda BachiiD· 1 shared Andréia Silva de OliveiraiD· 1 shared Cassiane Dezoti· 1 shared Cinthya dos Santos CirqueiraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Bianca CastinoORCID

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2 papers

Recent·Most cited

Temporal Dynamics of Kidney Mitochondrial Dysfunction in Type 2 Diabetes: Analysis of the Goto-Kakizaki Model.

Bianca Castino, Luciana Jorge, Alef AC Santos, André Luís Lacerda Bachi, Fernanda Teixeira Borges

This study examines the temporal progression of mitochondrial dysfunction in T2DM using GK rats, revealing an adaptive phase followed by failure and identifying a critical therapeutic window between 21 and 60 days.

bioRxiv · Dec 27, 2025 · PreprintCell Biology

Isoflavone treatment attenuates cardiovascular-kidney-metabolic (CKM) syndrome symptoms in an experimental model of ovariectomized rats.

Thaís de Souza Lima, Edson de Andrade Pessoa, Amaro Nunes Duarte Neto, Cinthya dos Santos Cirqueira, Márcia Bastos Convento, Bianca Castino, Andréia Silva de Oliveira, Alef AC Santos, Adriana Aparecida Ferraz Carbonel, Cassiane Dezoti, Maria de Fatima Vattimo, Fernanda Teixeira Borges

This study shows that soy isoflavones reduce systolic blood pressure, improve lipid and glycemic profiles, and partially preserve renal function in ovariectomized rats on a high-fat diet.

bioRxiv · Dec 25, 2025 · PreprintPathology