Increased bone inflammation in type 2 diabetes and obesity correlates with Wnt signaling downregulation and reduced bone strength
Giulia Leanza, Malak Faraj, Francesca Cannata, Viola Viola, Niccolò Pellegrini, Flavia Tramontana, Claudio Pedone, Gianluca Vadalà, Alessandra Piccoli, Rocky Strollo, Francesca Zalfa, Roberto Civitelli, Mauro Maccarrone, Rocco Papalia, Nicola Napoli
This study finds that inflammation in bone of T2D and obesity patients is linked to reduced Wnt signaling and lower bone strength.
bioRxiv · Sep 26, 2024 · PreprintBiochemistry