Hierarchical effects of pro-inflammatory cytokines on the post-influenza susceptibility to pneumococcal coinfection
Stefanie Duvigneau, Niharika Sharma-Chawla, Alessandro Boianelli, Sabine Stegemann-Koniszewski, Van Kinh Nguyen, Dunja Bruder, Esteban A. Hernandez-Vargas
This study identifies IFN-gamma as a key cytokine promoting bacterial growth during post-influenza pneumococcal coinfection, challenging existing beliefs about TNF and nutrient availability.
bioRxiv · Jun 24, 2016Immunology