Genomic Basis of Multiple Myeloma Subtypes from the MMRF CoMMpass Study
Sheri Skerget, Daniel Peñaherrera, Ajai Chari, Sundar Jagannath, David Samuel DiCapua Siegel, Ravi Vij, Gregory Joshua Orloff, Andrzej J. Jakubowiak, Rubén Niesvizky, Darla Liles, Jesús G. Berdeja, Moshe Yair Levy, Jeffrey Lee Wolf, Saad Z. Usmani, The MMRF CoMMpass Network, , Jonathan J. Keats
The paper identifies genomic subtypes of multiple myeloma using the MMRF CoMMpass study and finds that 25.5% of patients transition to a high-risk expression subtype at progression, which expresses immunotherapy targets.
medRxiv · Aug 2, 2021 · PreprintGenetic & Genomic Medicine