Defining amino acid pairs as structural units suggests mutation sensitivity toadjacent residues
Aviv A. Rosenberg, Nitsan Yehishalom, Ailie Marx, Alex Bronstein
The paper analyzes protein structures to show that amino acid pairs have conformational preferences and that mutations' effects on protein stability depend on their adjacent amino acid context.
bioRxiv · Oct 23, 2022 · PreprintMolecular Biology