Aviv A. Rosenberg

Statistical signals indicate a dependence between amino acid backbone conformation and the translated synonymous codon

The paper reanalyzes data showing codon-dependent differences in backbone conformation in E. coli, using corrected statistical methods and finding consistent small p-values.

Seeing Double: Molecular dynamics simulations reveal the stability of certain alternate protein conformations in crystal structures

The paper uses molecular dynamics simulations to show that proteins can adopt dual, transiently stable conformations, which current prediction methods fail to capture.

Defining amino acid pairs as structural units suggests mutation sensitivity toadjacent residues

The paper analyzes protein structures to show that amino acid pairs have conformational preferences and that mutations' effects on protein stability depend on their adjacent amino acid context.