Alex Liqi Lai

Critical Negatively Charged Residues Are Important for the Activity of SARS-CoV-1 and SARS-CoV-2 Fusion Peptides

This study identifies critical negatively charged residues in SARS-CoV-1 and SARS-CoV-2 fusion peptides that are essential for Ca2+ binding and membrane ordering activity.

SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca2+

This study compares the membrane perturbation effects of SARS-CoV-2 and SARS-CoV fusion peptides, showing SARS-2 has greater membrane ordering and Ca2+ dependence.