Author

Alexander Vaughan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Adam Kepecs· 1 shared David A. Tuveson· 1 shared Dawid D. Nowak· 1 shared Frank Stegmeier· 1 shared Lloyd C. Trotman· 1 shared Nitin H. Shirole· 1 shared Raffaella Sordella· 1 shared Serif Senturk· 1 shared

Activity by Year

2015-2015 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Adam Kepecs

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1 paper

Recent·Most cited

A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro and in vivo.

Serif Senturk, Nitin H. Shirole, Dawid D. Nowak, Vincenzo Corbo, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Adam Kepecs, Frank Stegmeier, Raffaella Sordella

This paper introduces a method to temporally control Cas9 expression using a destabilizing domain, enabling precise gene editing and functional interaction studies in vitro and in vivo.

bioRxiv · Jul 28, 2015 · PreprintBioengineering