Combined inactivation of RB and Hippo pathways converts differentiating photoreceptors into eye progenitor cells through derepression of homothorax
Alexandra E. Rader, Battuya Bayarmagnai, Maxim V. Frolov
The paper shows that inactivating RB and Hippo pathways in Drosophila photoreceptors causes dedifferentiation by derepressing homothorax, revealing their cooperative role in maintaining neuronal identity.
Developmental Cell · Oct 16, 2023Peer-reviewedDevelopmental Biology