GenomicsBMC GenomicsPeer-reviewed
Pan-Cancer Analysis Reveals Technical Artifacts in The Cancer Genome Atlas (TCGA) Germline Variant Calls
Alexandra R. Buckley, Kristopher A. Standish, Kunal Bhutani…·Nicholas J. Schork
This study identifies technical artifacts in TCGA germline variant calls, showing how batch effects from DNA amplification confound germline-tumor type associations and recommends removing amplified DNA samples.
43 citations