African Pan Genome Contigs Expose Biologically Relevant Sequence Still Hidden from Human Reference Frameworks
Rachel N. Martini, Abdulfatai Tijjani, Kyriaki Founta, Daniel Cha, Alexandria Awai, Sebastian Maurice, Jason A. White, Christopher E. Mason, Isidro Cortés‐Ciriano, Nicolas Robine, Onyinye Balogun, Nyasha Chambwe, Melissa Boneta Davis
The paper identifies African Pan Genome contigs that are missing from current human reference genomes, showing they contain functionally relevant sequences and are enriched in African ancestry.
bioRxiv · Aug 15, 2025 · PreprintGenomics