Discovery 4.0: An Escape-Aware Computational Platform for Resistance-Proofed Chimeric Antigen Receptor Design
Alireza Daneshvar, Rakhshan Mashayekhi, Mohammadhossein Sharifnia
Discovery 4.0 is a computational platform that designs CAR constructs resistant to antigen escape, achieving a 98.1% reduction in escape compared to monospecific controls.
bioRxiv · May 27, 2026 · PreprintCancer Biology