Age-Dependent Changes in the Progenitor Translatome Coordinated in part by Tsc1 Increase Perception of Signaling Inputs to End Nephrogenesis
Alison E. Jarmas, Eric W. Brunskill, Praneet Chaturvedi, Nathan Salomonis, Raphael Kopan
The paper shows age-dependent changes in nephron progenitor translation and signaling that influence nephrogenesis timing, with Tsc1 affecting Wnt signaling balance.
Nature Communications · Nov 3, 2021Peer-reviewedDevelopmental Biology