Structural basis for acyl group discrimination by human Gcn5L2
Alison E. Ringel, Cynthia Wolberger
The paper determines the structures of human Gcn5L2 bound to propionyl-CoA and butyryl-CoA, revealing how it discriminates between acyl chain donors and explains its weak activity for longer acyl groups.
bioRxiv · Mar 11, 2016Biophysics