The post-translational modification profile of TAR DNA-Binding Protein (TDP-43) in platelets of patients with Alzheimer's disease: An exploratory study for blood-based biomarker development.
Qwynton Johnson, Mahan Hadjian, Alpha Bah, Sean Smith, Edina Kosa, Abdulbaki Aǵbaş
This study identifies post-translational modifications of TDP-43 in platelets from Alzheimer's patients compared to controls, suggesting potential blood-based biomarkers for early diagnosis.
bioRxiv · Jan 29, 2023 · PreprintNeuroscience