Nanoscale decompaction of nucleosomal DNA revealed through multi-color super-resolution microscopy
Jason Otterstrom, Alvaro Castells Garcia, Chiara Vicario, Maria Pia Cosma, Melike Lakadamyali
The paper uses super-resolution microscopy to show that DNA is compacted by nucleosome groups (clutches) and that hyperacetylation reduces clutch DNA compaction, especially in regions with multiple nearby clutches.
bioRxiv · Nov 14, 2018 · PreprintCell Biology