Full-length next-generation sequencing of 11 HLA loci of more than 1000 individuals from clinical cohorts in East and West Africa
Yvonne V Rosario, Aviva Geretz, Lakshmi Rani Iyer, Philip K. Ehrenberg, Alya Tyson, Hannah Kibuuka, Fred Wabwire‐Mangen, Lucas Maganga, Abdulwasiu Bolaji Tiamiyu, Jonah K. Maswai, Josphat Kosgei, Frederick K. Sawe, Gary R. Matyas, Merlin Lee Robb, Julie A. Ake, Rasmi Thomas
The paper reports full-length NGS HLA genotyping of 1023 individuals from East and West Africa, identifying 371 unique alleles and 25 novel ones, including those with non-synonymous changes affecting peptide binding.
HLA · Jun 26, 2026Peer-reviewedGenetics