Author

Alyssa C Frazee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:simulation· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Andrew E Jaffe· 3 shared Ben LangmeadiD· 3 shared Jeffrey Leek· 2 shared Abhinav NelloreiD· 1 shared Christopher WilksiD· 1 shared Geo Pertea· 1 shared Jeffrey T Leek· 1 shared Leonardo Collado Torres· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioinformatics

Andrew E Jaffe

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3 papers

Recent·Most cited

Flexible expressed region analysis for RNA-seq with derfinder

Leonardo Collado Torres, Abhinav Nellore, Alyssa C Frazee, Christopher Wilks, Michael I Love, Ben Langmead, Rafael A Irizarry, Jeffrey Leek, Andrew E Jaffe

The paper introduces derfinder, a tool for RNA-seq analysis that identifies differentially expressed regions at single base resolution without relying on gene annotations, showing it works well with incomplete annotations and large datasets.

Nucleic Acids Research · Sep 29, 2016Peer-reviewedBioinformatics

Flexible analysis of transcriptome assemblies with Ballgown

Alyssa C Frazee, Geo Pertea, Andrew E Jaffe, Ben Langmead, Steven L Salzberg, Jeffrey T Leek

The paper introduces Ballgown, a tool for analyzing transcriptome assemblies from RNA-seq data, focusing on gene structure reconstruction and expression analysis.

Nature Biotechnology · Mar 6, 2015Peer-reviewedBioinformatics

Polyester: simulating RNA-seq datasets with differential transcript expression

Alyssa C Frazee, Andrew E Jaffe, Ben Langmead, Jeffrey Leek

Polyester simulates RNA-seq data with differential transcript expression to evaluate statistical methods for differential expression analysis.

bioRxiv · Dec 12, 2014Bioinformatics