Molecular regulation of PPARγ/RXRα signaling by the novel cofactor ZFP407
Alyssa Charrier, Jeremiah Ockunzzi, Leighanne R. Main, Siddharth V. Ghanta, David A. Buchner
The paper identifies ZFP407 as a novel PPARγ cofactor that regulates adipocyte function through direct DNA binding and interaction with the PPARγ/RXRα complex, independent of post-translational modifications.
PLoS ONE · May 23, 2024Peer-reviewedMolecular Biology