Author

Alyssa R. Bogar

The University of Texas Medical Branch at Galveston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Michelle C. WardiD· 3 shared E. Renee MatthewsiD· 2 shared Sayan PauliD· 2 shared Emma M PfortmilleriD· 1 shared John D. HurleyiD· 1 shared José A GutiérreziD· 1 shared Jose A. Gutierrez· 1 shared José A. Gutiérrez· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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3 shared papersGenomics

Michelle C. WardORCID

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3 papers

Recent·Most cited

Progressive suppression of DNA repair genes with persistent p53 activation in Doxorubicin-treated cardiomyocytes

Emma M Pfortmiller, José A Gutiérrez, Alyssa R. Bogar, Michelle C. Ward

The paper profiles gene expression in DOX-treated cardiomyocytes over time, identifying a chronic gene signature enriched for p53 target genes and DNA damage response genes.

G3 Genes Genomes Genetics · Jun 22, 2026Peer-reviewedGenomics

Topoisomerase II inhibitors CX-5461 and Doxorubicin differ in their cardiotoxicity profiles

Sayan Paul, Jose A. Gutierrez, Alyssa R. Bogar, E. Renee Matthews, Michelle C. Ward

This study compares the cardiotoxicity of CX-5461 and Doxorubicin in iPSC-derived cardiomyocytes, finding CX is less cytotoxic and induces fewer gene expression changes.

G3 Genes Genomes Genetics · Jan 16, 2026Peer-reviewedGenomics

Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci

E. Renee Matthews, Raodatullah O. Abodunrin, John D. Hurley, Sayan Paul, José A. Gutiérrez, Alyssa R. Bogar, Michelle C. Ward

This study shows anthracyclines alter chromatin accessibility in cardiomyocytes, overlapping with cardiovascular disease risk loci.

PLoS Genetics · Oct 14, 2025Peer-reviewedGenomics