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Amanda J Lea

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Genomics· 1

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Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:mixed model· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

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Jenny TungiD· 1 shared Xiang ZhouiD· 1 shared

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2015-2015 · peak 1/yr

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Recent·Most cited

A flexible, efficient binomial mixed model for identifying differential DNA methylation in bisulfite sequencing data

Amanda J Lea, Jenny Tung, Xiang Zhou

The paper introduces MACAU, a binomial mixed model for analyzing bisulfite sequencing data, showing improved power to detect differentially methylated sites in structured populations.

bioRxiv · Oct 14, 2015Genomics