Epigenetic and 3D genome reprogramming during the aging of human hippocampus
Nathan R. Zemke, Seo Yeon Lee, Sainath Mamde, Bing Yang, Nicole C. Berchtold, B. Maximiliano Garduño, Hannah S. Indralingam, Weronika M. Bartosik, Pik Ki Lau, Keyi Dong, Emily Hsu, Amanda Yang, Yasmine Tani, Chumo Chen, Qiurui Zeng, , Bing Ren
This study examines age-related changes in the human hippocampus using multi-omics data, revealing cell-type loss and epigenetic reprogramming linked to cognitive decline.
Science · Jul 23, 2026Peer-reviewedGenomics