IFN-γ Orchestrates Coordinated Immunosuppression in Head and Neck Squamous Cell Carcinoma Through JAK-STAT-IRF8 Signaling: A Transcriptome-Wide Computational Analysis
Amir Abdelhamid, Eslam E. Abd El-Fattah
The paper identifies IFN-γ-driven immunosuppressive mechanisms in HNSC through transcriptome-wide analysis, highlighting JAK-STAT-IRF8 signaling and key mediators like PDCD1LG2 and JAK2.
bioRxiv · Mar 29, 2026 · PreprintGenetics