Author

Eslam E. Abd El-Fattah

City Of Hope National Medical CenterORCID 0000-0003-2611-4797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Mohamed HammadiD· 2 shared Amir Abdelhamid· 1 shared Chia‐en A. ChangiD· 1 shared Karen Saida AboodyiD· 1 shared Kingsley Wu· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersCancer Biology

Mohamed HammadORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 22, 2026

CACNA1C as a Prognostic Biomarker and Therapeutic Target in High-Grade Serous Ovarian Cancer: Clinical Validation and Molecular Dynamics of Nifedipine Blockade

Mohamed Hammad, Kingsley Wu, Eslam E. Abd El-Fattah…·Chia‐en A. Chang

This paper identifies CACNA1C as a prognostic biomarker and therapeutic target in high-grade serous ovarian cancer, showing nifedipine suppresses tumor growth through calcium channel blockade.

DOI 10.64898/2026.04.19.719516

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 31, 2026

Tumor-Intrinsic IL-17 Signaling Correlates with Multimodal Resistance Phenotypes Following Oncolytic Adenovirus Challenge

Eslam E. Abd El-Fattah, Mohamed Hammad

This study identifies IL-17 signaling as a tumor-intrinsic factor associated with resistance to oncolytic adenovirus therapy, linked to stemness, metabolic changes, and reduced cell death.

DOI 10.64898/2026.03.27.714871

mousebulk RNA-seq

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GeneticsbioRxivPreprintMar 29, 2026

IFN-γ Orchestrates Coordinated Immunosuppression in Head and Neck Squamous Cell Carcinoma Through JAK-STAT-IRF8 Signaling: A Transcriptome-Wide Computational Analysis

Amir Abdelhamid, Eslam E. Abd El-Fattah

The paper identifies IFN-γ-driven immunosuppressive mechanisms in HNSC through transcriptome-wide analysis, highlighting JAK-STAT-IRF8 signaling and key mediators like PDCD1LG2 and JAK2.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky