Platelet-derived CXCL7 induces neutrophil extracellular traps via CXCL7/CXCR2 axis, exacerbating the pathogenesis of diabetic retinopathy
Bishamber Nath, Suraj Bhausaheb Mungase, Ritu Sharaya, Anshu Gupta, Amir Ali, Mahesh J. Kulkarni, Manabjyoti Barman, Sudhagar Selvaraj, Amit Kumar Yadav, Ramu Adela
This study shows that platelet-derived CXCL7 promotes NET formation via the CXCR2 axis in diabetic retinopathy, worsening disease progression.
bioRxiv · Jan 24, 2026 · PreprintImmunology