Dysregulation of Neuroprotective Lipoxin Pathway in Astrocytes in Response to Cytokines and Ocular Hypertension
Shruthi Karnam, Shubham Maurya, Elainna Ng, Amodini Choudhary, Arzin Thobani, John G. Flanagan, Karsten Gronert
This study investigates how the lipoxin pathway in astrocytes is dysregulated in response to cytokines and ocular hypertension, showing that LXB4 treatment mitigates astrocyte reactivity and restores lipoxin generation.
Acta Neuropathologica Communications · Apr 12, 2024Peer-reviewedNeuroscience