The role of mu opioid receptors on excitatory and inhibitory neurons in the rostral ventromedial medulla in neuropathic pain
Jamie C. Moffa, Amy Gao, Vani Kalyanaraman, Monique R. Heitmeier, Bryan A. Copits
This study investigates the role of mu opioid receptors in glutamatergic and GABAergic neurons of the rostral ventromedial medulla in neuropathic pain, finding that MOR signaling modulates early hypersensitivity but not chronic pain intensity.
bioRxiv · Sep 1, 2026 · PreprintNeuroscience