Predicting the effect of non-coding mutations on single-cell DNA methylation using deep learning
Zhe Liu, An Gu, Yihang Bao, Guan Ning Lin
This paper introduces Methven, a deep learning framework that predicts non-coding mutation effects on DNA methylation at single-cell resolution, showing superior performance in prioritizing functional mutations.
bioRxiv · Sep 3, 2024 · PreprintBioinformatics