Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4
Simone-Franziska Glaser, Andre Brezski, Nina Baumgarten, Marius Klangwart, Andreas W. Heumüller, Ranjan Kumar Maji, Matthias S. Leisegang, Stefan Guenther, Christoph M. Zehendner, David John, Marcel H. Schulz, Kathi Zarnack, Stefanie Dimmeler
This study identifies circPLOD2 as a hypoxia-regulated circRNA that modulates pericyte function by regulating KLF4, affecting proliferation and vascular interactions.
Cell Reports · Jul 21, 2023Peer-reviewedMolecular Biology