A quantitative imaging framework reveals density-dependent GPCR oligomerization and organization in living cells
Céline Delaitre, Andre Dias, Nikolaj K. Brinkenfeldt, Elisa Pons, Mathew Mungra, Gabriella von Scheel von Rosing, Jacob Hallberg, François Dupuis, Sandra Lecat, Poul Martin Bendix, Morten Meldal, Mette M. Rosenkilde, Signe Mathiasen, Karen Laurence Martinez
This paper introduces a quantitative imaging framework to study GPCR oligomerization in living cells, revealing density-dependent monomer-dimer equilibria and apparent affinities for dimerization.
bioRxiv · May 21, 2026 · PreprintBiophysics