Beta2* Nicotinic Receptors Regulate Exploratory and Social Behavior Through Functionally Distinct Neuronal Populations
Alice Abbondanza, Jan Elias, Chandani R. Verma, Amanda Rosanna Alves Barboza, Martin Capek, Trisha Jigar Dhabalia, Andrea Grigelova, Sylvie Dumas, Veronique Bernard, Helena Janickova
Beta2 nicotinic receptor knockdown in Htr3a-Cre mouse interneurons gave strong hypersociability; prefrontal NPY-Cre neurons, weaker effects (reduced social preference); striatal NPY neurons, slight effects mostly opposite to those.
bioRxiv · Sep 25, 2026 · PreprintNeuroscience✦ In-depth digest