Global Huntingtin Knockout in Adult Mice Leads to Fatal Neurodegeneration that Spares the Pancreas
Robert M. Bragg, Ella W. Mathews, Andrea Grindeland, Jeffrey P. Cantle, David Howland, Tom Vogt, Jeffrey B. Carroll
This study shows that global Htt knockout in adult mice causes neurodegeneration and subcortical calcification but not pancreatitis, and increases neurofilament light chain levels.
Life Science Alliance · Jul 25, 2024Peer-reviewedNeuroscience