Cell Tree Rings: the structure of somatic evolution as a human aging timer
Attila Csordás, Botond Sipos, Terézia Kurucová, Andrea Volfova, Frantisek Zamola, Boris Tichý, Damien G. Hicks
This paper introduces a method to estimate biological age using cell lineage trees derived from somatic mutations in scRNA-seq data, showing strong correlation with chronological age.
GeroScience · Jan 3, 2024Peer-reviewedGenomics