Genetic control of Group 3 (K96) capsule synthesis and complement resistance in an extraintestinal pathogenic Escherichia coli ST69 strain
Rachael J. David Prince, Rajesh Bogati, Titan Lytle, Andres Collado Silva, Rachael A. LeBaron, Tiana Sorge, Michael A. Olson, Eric Wilson, David L. Erickson
This study identifies genetic factors controlling Group 3 K96 capsule synthesis in ExPEC strain M12, showing its role in complement resistance and revealing phase-variable control and OxyR-dependent regulation.
bioRxiv · Sep 19, 2025 · PreprintMicrobiology