Author

Andrew Hesse

The Jackson Laboratory for Genomic Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Abhijit RathiD· 1 shared Akriti Mishra· 1 shared Chaoran HuiD· 1 shared Christopher D. HeineniD· 1 shared Gregory Omerza· 1 shared Honey V. ReddiiD· 1 shared James P. Grady· 1 shared Kevin KellyiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Abhijit RathORCID

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1 paper

Recent·Most cited

Functional Interrogation of Lynch Syndrome Associated MSH2 Missense Variants Using CRISPR-Cas9 Gene Editing in Human Embryonic Stem Cells

Abhijit Rath, Akriti Mishra, Victoria Duque Ferreira, Chaoran Hu, Gregory Omerza, Kevin Kelly, Andrew Hesse, Honey V. Reddi, James P. Grady, Christopher D. Heinen

The paper functionally tests MSH2 missense variants in Lynch syndrome using CRISPR-Cas9 in human embryonic stem cells to assess their impact on DNA repair and MMR function.

Human Mutation · Jun 25, 2019Peer-reviewedGenomics