Unveiling Candidate Drivers in Cancer Progression Using Somatic-IV Analysis
Wei Zhang, Saba Ghaffari, Andrew J. Browne, Carlos Macintosh, Xiaoyu Lu, Ha M. Dang, Gonzalo Lopez, Kai Wang
This paper introduces Somatic-IV, a method to identify candidate driver genes in cancer by integrating genetic, transcriptomic, and clinical data, and finds ZBED2 and CSNK2A2 as potential drivers in pancreatic and colorectal cancers.
bioRxiv · Feb 20, 2025 · PreprintBioinformatics