A prefrontal network model operating near steady and oscillatory states links spike desynchronization and synaptic deficits in schizophrenia
David A. Crowe, Andrew Willow, Rachael Keir Blackman, Adele L. DeNicola, Matthew V. Chafee, Bagrat R. Amirikian
This paper develops a prefrontal network model to show how NMDAR synaptic deficits in schizophrenia disrupt spike timing and prevent network state transitions.
eLife · Dec 21, 2023Peer-reviewedNeuroscience