Pathologist-interpretable breast cancer subtyping and stratification from AI-inferred nuclear features
Ranjan Kumar Barman, Saugato Rahman Dhruba, Danh-Tai Hoang, Eldad David Shulman, Emma M. Campagnolo, Andy T. Wang, Stephanie A. Harmon, Tom C. Hu, Antonios Papanicolau‐Sengos, MacLean P. Nasrallah, Kenneth Aldape, Eytan Ruppin
This paper introduces EXPAND, an interpretable AI model that predicts breast cancer subtypes and survival using nuclear features, achieving performance comparable to black-box models.
bioRxiv · Sep 4, 2025 · PreprintBioinformatics