Exploration of inositol 1,4,5-trisphosphate (IP3) regulated dynamics of N-terminal domain of IP3 receptor reveals early phase molecular events during receptor activation
Aneesh Chandran, Xavier Chee Wezen, David L. Prole, Taufiq Rahman
This study uses molecular dynamics simulations to uncover the dynamic interactions and conformational changes in the N-terminal domain of IP3 receptor during IP3 binding, revealing key molecular events in receptor activation.
Scientific Reports · Feb 21, 2019Peer-reviewedBioinformatics