Zebrafish adamtsl4 knockout recapitulates key features of human ADAMTSL4-related diseases: a gene involved in extracellular matrix organization, cell junctions and development
Angel Tevar, José‐Daniel Aroca‐Aguilar, Raquel Atiénzar-Aroca, Ana Isabel Ramirez, José A. Fernández‐Albarral, Julio Escribano
This study creates a zebrafish adamtsl4 knockout model that recapitulates key human ADAMTSL4-related disease features, including ocular and skeletal abnormalities, and shows its role in ECM organization and development.
Experimental Eye Research · Aug 8, 2025Peer-reviewedGenetics