HolistiC: Leveraging Hi-C and Whole Genome Shotgun Sequencing for Double Minute Chromosome Discovery
Matthew Hayes, Angela Nguyen, Rahib Islam, Caryn Butler, Ethan Tran, Derrick Mullins, Chindo Hicks
HolistIC integrates Hi-C and WGS data to accurately predict double minutes in cancer genomes, resolving ambiguities from overlapping amplicon coordinates.
Bioinformatics · Dec 4, 2021Peer-reviewedBioinformatics