Myosin light chain proteins cooperatively promote sarcomere growth in fast-twitch muscle
Tayo E Adekeye, Troy Hupper, Teresa Easterbrooks, Emily M. Teets, Emily A. Tomak, Sadie Waterman, Kailee Sprague, Angelina White, Maddison Coffin, Daniel K. Tanaka, Sabrina Varga, Mason Soares, Sarah J. Shepherd, Jared D Austin, Dmitrii Krivorotko, , Jared Coffin Talbot
This study shows that Mylpf proteins are essential for sarcomere growth in fast-twitch muscle, with their dosage affecting sarcomere formation and myofilament localization.
Nature Communications · Jun 4, 2026Peer-reviewedDevelopmental Biology