Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis
Joseph Jacob, Brian J. Bartholmai, Coline H.M. van Moorsel, Srinivasan Rajagopalan, Anand Devaraj, Hendrik W. van Es, Teng Moua, Frouke T. van Beek, Ryan Clay, Marcel Veltkamp, Maria A. Kokosi, Angelo De Lauretis, Eoin P. Judge, Teresa Jacob, Tobias Peikert, , Athol Umfrey Wells
This study evaluates computer-derived CT variables (CALIPER vessel-related structures) as predictors of outcome in IPF, finding they outperform FVC decline in predicting prognosis and increasing trial power when used as co-endpoints.
European Respiratory Journal · Jun 13, 2019Peer-reviewedBioinformatics