Insertion and Anchoring of HIV-1 Fusion Peptide into Complex Membrane Mimicking Human T-cell
Mingfei Zhao, Laura J. S. Lopes, Harshita Sahni, Anju Yadav, Hung Nguyen Do, Tyler J. Reddy, César A. López, Chris Neale, Sandrasegaram Gnanakaran
This study uses molecular dynamics simulations to investigate how the HIV-1 fusion peptide inserts and anchors into a T-cell membrane mimic, identifying a critical motif for fusion.
The Journal of Physical Chemistry B · Dec 13, 2024Peer-reviewedBiophysics