Author

Anna Hlubinová

Comenius University Bratislava

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Systems Biology· 2

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Approach:statistical model· 2

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Abhyudai SinghiD· 2 shared Pavol BokesiD· 2 shared

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2022-2025 · peak 1/yr

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Abhyudai SinghORCID

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Systems BiologybioRxivPreprintMay 20, 2025

Fluctuation Test with Phenotypic Switching: A Unified Stochastic Approximation Framework

Anna Hlubinová, Pavol Bokes, Abhyudai Singh

The paper develops a stochastic framework for analyzing fluctuation tests with phenotypic switching, showing that stable distributions or large deviations theory can approximate the probability distribution of tolerant cells depending on switching frequency.

DOI 10.1101/2025.05.20.655090

statistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintDec 26, 2022

Reversibility of resistance in a fluctuation test experiment modifies the tail of the Luria-Delbrück distribution

Pavol Bokes, Anna Hlubinová, Abhyudai Singh

The paper modifies the Luria-Delbrück distribution by allowing resistance reversibility, showing the tail deviates from the Landau distribution's power law decay.

DOI 10.1101/2022.12.26.521941

statistical model

𝕏 PostBluesky