Synthetic BiologyThe Journal of AntibioticsPeer-reviewed
An Unusual Follower Peptide is Required for Biosynthesis of the Antibiotic Lasso Peptide Triculamin
Tiziana Svenningsen, Aske Merrild, Asger Buchbjerg Petersen…·Thomas Tørring
This study identifies an essential follower peptide for triculamin biosynthesis and shows its role in enzyme-substrate complex formation and substrate promiscuity.
DOI 10.1038/s41429-026-00966-4