A strategy to detect metabolic changes induced by exposure to chemicals from large sets of condition-specific metabolic models computed with enumeration techniques
Louison Fresnais, Olivier Périn, Anne Riu, Romain Grall, Alban Ott, Bernard Fromenty, Jean-Clément Gallardo, Maximilian Stingl, Clément Frainay, Fabien Jourdan, Nathalie Poupin
This paper introduces a strategy to detect metabolic changes from chemical exposure using transcriptomics data and metabolic models, identifying potential mechanisms of action in vitro.
bioRxiv · Jun 30, 2023 · PreprintBioinformatics