Cell-specific transcription dysregulation in human Huntington's disease-positive developing striatum
Sophie V. Precious, Oliver J.M. Bartley, Phoebe Linehan, Alys N Aston, Rachel Hills, Anne-Marie McGorrian, Vincent Dion, Anne Rosser
The paper identifies transcriptional changes in fetal HD striatal tissue using single-cell RNA sequencing, revealing molecular features of HD pathology present during early development.
bioRxiv · Jun 19, 2026 · PreprintNeuroscience