Author

Oliver J.M. Bartley

Cardiff UniversityORCID 0000-0001-7563-9464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. E. RosseriD· 2 shared Sophie V. Precious· 2 shared Alys N AstoniD· 1 shared Anne-Marie McGorrian· 1 shared Mariah J. LelosiD· 1 shared Ngoc Nga Vinh· 1 shared Nigel M. WilliamsiD· 1 shared Phoebe Linehan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

A. E. RosserORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 19, 2026

Cell-specific transcription dysregulation in human Huntington's disease-positive developing striatum

Sophie V. Precious, Oliver J.M. Bartley, Phoebe Linehan…·Anne Rosser

The paper identifies transcriptional changes in fetal HD striatal tissue using single-cell RNA sequencing, revealing molecular features of HD pathology present during early development.

DOI 10.64898/2026.06.19.733377

humanscRNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 25, 2024

Defining the Limits of hPSC Derived Models: hPSC-MSNs Fail to Recapitulate Authentic Striatal Identity

Oliver J.M. Bartley, Ngoc Nga Vinh, Mariah J. Lelos…·A. E. Rosser

This study shows that hPSC-derived medium spiny neurons (hPSC-MSNs) do not fully replicate the epigenetic and transcriptional features of authentic fetal MSNs, highlighting limitations in their fidelity.

DOI 10.1101/2024.06.25.600518

humanDNA methylation

𝕏 PostBluesky